Behandling av ADHD (Attention-deficit/hyperactivity disorder) hos vuxna, med centralstimulerande medel [Treatment of ADHD (Attention-Deficit/Hyperactivity Disorder) in adults with central stimulants]
The Regional Health Technology Assessment Centre (HTA-centrum)
Citation
The Regional Health Technology Assessment Centre (HTA-centrum). Behandling av ADHD (Attention-deficit/hyperactivity disorder) hos vuxna, med centralstimulerande medel. [Treatment of ADHD (Attention-Deficit/Hyperactivity Disorder) in adults with central stimulants] Gothenburg: The Regional Health Technology Assessment Centre (HTA-centrum). HTA-rapport 2008:10. 2008
Authors' objectives
Are ADHD symptoms positively affected, in adult patients with ADHD, treated with methylphenidate or its derivatives, compared with placebo?
Authors' conclusions
Short-term treatment with methylphenidate or its derivatives has a significantly better effect than placebo on ADHD symptoms, in adult patients with ADHD diagnosis (evidence level 2, moderately strong scientific evidence). Effect size is considered moderate and data on long-term effects are lacking. Side effects are considered to be acceptable, with a question mark regarding abuse risk. The target population is considered to be large, and the drugs are relatively expensive. Moreover, the identification of the right patients for treatment will require an extensive and costly diagnostic workup. Introduction of the treatment is expected to generate an annual cost of 50-70 million SEK, which may create significant risks of displacement within psychiatry. There is a great need for long-term studies.
Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Agents; Central Nervous System Stimulantss
Language Published
Swedish
Country of organisation
Sweden
English summary
An English language summary is available.
English Summary
English summary available
Address for correspondence
The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden Email: hta-centrum@vgregion.se