This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database.

Nachtnebel A, Reinsperger I. Perkutane mitralklappenintervention mittels mitralclip bei mitralklappeninsuffizienz. [Percutaneous repair of mitral regurgitation with the MitraClip] . Vienna: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBIHTA). Decision Support Dokument Nr: 41 – 1. Update. 2012

Percutaneous mitral valve repair using the MitraClip® device intends to reduce severity of mitral valve regurgitation (MR) in patients with moderate-to-severe or severe MR. It might be used for patients eligible for surgery as well as for those at high surgical risk. Therapeutic aim of this intervention is to reduce symptoms of MR, to improve NYHA-Class and quality-of-life and to prolong life.

Due to methodological limitations of the RCT and due to the uncontrolled study design of the before-after study, the quality of evidence is low-medium for operable patients. For inoperable patients/patients at high surgical risk the quality of evidence of the included before-after studies is very low due their uncontrolled study design. Overall, the available evidence is currently insufficient to assess the efficacy and safety of MitraClip® in comparison to the respective standard therapy for patients with MR. Therefore, the inclusion into the hospital benefit catalogue is not recommended, either for operable or for inoperable patients.

Subject indexing assigned by CRD

Echocardiography, Doppler, Color; Echocardiography, Transesophageal; Humans; Mitral Valve Insufficiency

English

Austria

An English language summary is available.

Ludwig Boltzmann Institute fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7 rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99 Email: anna.nachtnebel@hta.lbg.ac.at

32012000781

16/10/2012