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Vitamin D supplementation in patients with active or latent tuberculosis |
Lönnermark E, Dotevall L, Fjällbrant H, Kötz K, Sjövall H , Sundell N, Svanberg T, Trollfors B, Wikberg Adania U, Sjögren P |
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Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Lönnermark E, Dotevall L, Fjällbrant H, Kötz K, Sjövall H , Sundell N, Svanberg T, Trollfors B, Wikberg Adania U, Sjögren P. Vitamin D supplementation in patients with active or latent tuberculosis. Gothenburg: The Regional Health Technology Assessment Centre (HTA-centrum). HTA-rapport 2012:53. 2012 Authors' objectives Does vitamin D supplementation, as compared to no treatment or placebo, reduce mortality, slow progression of disease, reduce disease susceptibility or increase the quality of life in patients with active or latent TB infection? Authors' conclusions Vitamin D supplementation has no significant effect on mortality (low quality of evidence), or disease progression in patients with active TB (very low quality of evidence). No articles were identified studying the effect of vitamin D supplementation on quality of life in patients with active TB. Neither was any studies identified with these outcomes in patients with latent TB. In patients with very low vitamin D levels (25OHD levels below 30-50 nmol/L), treatment is probably indicated irrespective of TB status but this aspect was not analysed in the current HTA report. Indexing Status Subject indexing assigned by CRD MeSH Dietary Supplementss; Mycobacterium tuberculosis; Tuberculosis; Vitamin D; Vitamins Language Published English Country of organisation Sweden English summary An English language summary is available. Address for correspondence The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden Email: hta-centrum@vgregion.se AccessionNumber 32013000122 Date abstract record published 13/03/2013 |
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