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Treatments for seasonal allergic rhinitis |
Glacy J, Putnam K, Godfrey S, Falzon L, Mauger B, Samson D, Aronson N |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Glacy J, Putnam K, Godfrey S, Falzon L, Mauger B, Samson D, Aronson N. Treatments for seasonal allergic rhinitis. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 120. 2013 Authors' objectives This review compared the effectiveness and common adverse events of medication
classes used to treat seasonal allergic rhinitis (SAR) in adolescents and adults, in pregnant
women, and in children. We sought to compare the following classes of drugs: oral and nasal
antihistamines and decongestants; intranasal corticosteroids, mast cell stabilizers (cromolyn), and
anticholinergics (ipratropium); oral leukotriene receptor antagonists (montelukast); and nasal
saline. Authors' conclusions Several effectiveness comparisons demonstrated similarity of treatments for
selected outcomes. For most harms comparisons, the evidence was insufficient. Conclusions
were limited by (1) lack of comparative evidence for all drugs within each class and (2) lack of
evidence on the magnitude of symptom change that constitutes a minimal clinically important
difference. Indexing Status Subject indexing assigned by CRD MeSH Humans; Rhinitis, Allergic, Seasonal Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence AHRQ, Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA Email: AHRQTAP@ahrq.hhs.gov AccessionNumber 32013000718 Date abstract record published 14/10/2013 |
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