Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Lin JS, Olson CM, Johnson ES, Senger CA, Soh CB, Whitlock EP. The ankle brachial index for peripheral artery disease screening and cardiovascular disease prediction in
asymptomatic adults: a systematic evidence review for the U.S. Preventive Services Task Force. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Synthesis No. 100. 2013 Authors' objectives We conducted a systematic evidence review on the diagnostic and prognostic value of the resting ankle-brachial index (ABI) in unselected populations. This review also examined the benefit and harms of treating generally asymptomatic persons with peripheral artery disease (PAD). We conducted this review to support the U.S. Preventive Services Task Force in updating its recommendation on screening for PAD. Authors' conclusions There is very limited evidence examining the diagnostic accuracy of the ABI as a screening tool (one study) or examining the treatment of generally asymptomatic persons with PAD or a low ABI (two trials). However, there is a large body of evidence (18 population-based cohorts) suggesting that a low ABI is independently associated with increased CAD and CVD risk, after adjusting for FRS factors. Despite this association, the magnitude of risk reclassification of ABI in addition to FRS is still unclear and is likely small. The net
reclassification may have the largest impact among persons age 65 years and older and persons at the thresholds of FRS risk categories. Indexing Status Subject indexing assigned by CRD MeSH Ankle Brachial Indexs; Cardiovascular Diseases; Peripheral Arterial Disease Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence AHRQ, Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA Email: AHRQTAP@ahrq.hhs.gov AccessionNumber 32013000755 Date abstract record published 25/10/2013 |