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| Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer |
| Fortmann SP, Burda BU, Senger CA, Lin J, Beil T, O'Connor E, Whitlock EP |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Fortmann SP, Burda BU, Senger CA, Lin J, Beil T, O'Connor E, Whitlock EP. Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report No. 108. 2013 Authors' objectives To systematically review evidence for the use of multivitamins or single nutrients and functionally related nutrient pairs for the prevention of CVD and cancer in the general population (primary prevention). Authors' conclusions There are a limited number of trials examining the effects of dietary supplements on the primary prevention of CVD and cancer; the majority showed no effect in healthy populations. Clinical heterogeneity of included studies limits generalizability of results to the general primary care population. Results from trials in at-risk populations discourage additional studies for particular supplements (e.g., beta-carotene); however, future research in general primary care populations and on other supplements is required to address research gaps. Indexing Status Subject indexing assigned by CRD MeSH Cardiovascular Diseases; Dietary Supplements; Humans; Minerals; Neoplasms; Vitamins Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence AHRQ, Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA Email: AHRQTAP@ahrq.hhs.gov AccessionNumber 32014000080 Date abstract record published 20/01/2014 |
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