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Uso de cemento con antibióticos en la artroplastia primaria de cadera y rodilla [Use of antibiotic-loaded bone cement in primary hip and knee arthroplasty] |
Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A, Urtasun M |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A, Urtasun M. Uso de cemento con antibióticos en la artroplastia primaria de cadera y rodilla. [Use of antibiotic-loaded bone cement in primary hip and knee arthroplasty] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rápida N° 314. 2013 Authors' objectives The purpose of this report is to assess the evidence available on the efficacy, safety and coverage policy related issues on the use of antibiotic-loaded bone cement in primary hip and knee arthroplasty. Authors' conclusions The evidence found for primary THA was of moderate quality and it showed that ATB-loaded cement might add some clinical benefit to systemic prophylaxis, although there are no RCTs of adequate quality supporting this indication. The evidence found for TKAs was of good quality although contradictory regarding results. Some studies showed the benefits of adding ATB-loaded cement to the systemic antibiotic prophylaxis, however the most recent RCT, with the largest number of patients enrolled, found no clinical benefits associated to the use of antibiotic-loaded cement. In spite of the fact that evidence is not conclusive for THA and TKA, the clinical practice guidelines usually support its use, although in some cases they restrict it to patients considered at high risk. Indexing Status Subject indexing assigned by CRD MeSH Antibiotic Prophylaxiss; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Cements; Joint Prosthesis Language Published Spanish Country of organisation Argentina English summary An English language summary is available. Address for correspondence Institute for Clinical Effectiveness and Health Policy, Viamonte 2146 - 3 Piso, C1056ABH Ciudad de Buenos Aires, Argentina Tel: +54 11 49 66 00 82 Fax:+54 11 49 53 40 58 Email: info@iecs.org.ar AccessionNumber 32014000248 Date abstract record published 28/01/2014 |
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