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Profilaxis de enfermedad tromboembólica con heparinas de bajo peso molecular en pacientes adultos en internación domiciliaria [Prophylaxis for thromboembolic disease with low molecular weight heparins in adult patients in home care] |
Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Alcaraz A, Lopez A, Bardach A, Ciapponi A,
Urtasun M |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Alcaraz A, Lopez A, Bardach A, Ciapponi A,
Urtasun M. Profilaxis de enfermedad tromboembólica con heparinas de bajo peso molecular en pacientes adultos en internación domiciliaria. [Prophylaxis for thromboembolic disease with low molecular weight heparins in adult patients in home care] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rápida N° 274. 2012 Authors' objectives To assess the available evidence on the efficacy, safety and coverage policy related aspects about the use of LMWH vs. NFH for the prevention of VET, DVT, PE in patients immobilized at home health care due to conditions such as cancer, orthopedic surgeries or advanced age. Authors' conclusions No evidence was found on the subcutaneous use of NFH in preventing DVT-PE in immobilized patients in home care, after an orthopedic surgery, cancer or elderly. New studies will be necessary to determine its use in this population. About the use of LMWH in preventing DVT-PE after orthopedic surgery, cancer or in the elderly, the studies found presented an adequate level of evidence which shows that LMWHs are as efficacious as intravenous NFH, they have a simpler follow up and administration but they have a slight increase in the incidence of bleeding and they are more expensive. The indication of LMWH is at the same level as the other anticoagulation agents in hip or knee replacement, being the alternative of choice in facture of the hip. In case of high risk of bleeding after a major orthopedic surgery, mechanical prophylaxis is recommended. In both cancer and elderly patients, unless there are no added risk factors, the use of anticoagulation prophylaxis is not recommended. Indexing Status Subject indexing assigned by CRD MeSH Adult; Anticoagulants; Heparin, Low-Molecular-Weights; Orthopedic Nursing; Venous Thromboembolism Language Published Spanish Country of organisation Argentina English summary An English language summary is available. Address for correspondence Institute for Clinical Effectiveness and Health Policy, Viamonte 2146 - 3 Piso, C1056ABH Ciudad de Buenos Aires, Argentina Tel: +54 11 49 66 00 82 Fax:+54 11 49 53 40 58 Email: info@iecs.org.ar AccessionNumber 32014000280 Date abstract record published 30/01/2014 |
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