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Uso de toxina botulínica en pacientes con cefalea [Botulinum toxin for the treatment of headache] |
Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Alcaraz A, Lopez A, Bardach A, Ciapponi A, Romano M |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Alcaraz A, Lopez A, Bardach A, Ciapponi A, Romano M. Uso de toxina botulínica en pacientes con cefalea. [Botulinum toxin for the treatment of headache] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). 2011 Authors' objectives Evaluate the available evidence about the effectiveness, safety and insurance policy related to the use of TBA in patients with ME. MC, CST. Authors' conclusions TBA has not been proved to be superior to placebo for the prophylaxis treatment of chronic headache tension or episodic migraine. In general, its use is endorsed among patients who meet the criteria for chronic migraine set by the International Headache Society and who have failed or have intolerance of contraindications to other prophylactic agents. It should be noted that the benefit seen in studies in patients with CM , who promoted its adoption by the FDA and the various regulatory agencies was of low magnitude. These benefits include a reduction of -2.3 headache episodes per month compared to a baseline of 12, or in secondary outcomes (reduction in the number of headache days per month) -1.5 with a baseline of 20 days. These results, more than being statistically significant, are clinically irrelevant, implying a significant cost. Final publication URL www.iecs.org.ar Indexing Status Subject indexing assigned by CRD MeSH Botulinum Toxins; Headache Disorderss Language Published Spanish Country of organisation Argentina English summary An English language summary is available. Address for correspondence Institute for Clinical Effectiveness and Health Policy, Viamonte 2146 - 3 Piso, C1056ABH Ciudad de Buenos Aires, Argentina Tel: +54 11 49 66 00 82 Fax:+54 11 49 53 40 58 Email: info@iecs.org.ar AccessionNumber 32014000327 Date abstract record published 05/02/2014 |
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