Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Ketamine for adult patients who have suffered painful and traumatic injuries: a Review of Clinical Effectiveness, Cost-Effectiveness, Safety and Guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response - Summary with Critical Appraisal. 2014 Authors' conclusions One study failed to show a difference between ketamine and morphine for analgesic effect in a post hoc analysis of a subset of patients with head trauma. No published trials were identified examining the clinical effectiveness and safety of ketamine in adult patients who have suffered painful and traumatic eye injury. No published trials were identified examining the optimal dose of ketamine in adults with moderate to severe pain from traumatic injury who are conscious. No published trials were identified examining the safety of low dose ketamine as compared to fentanyl and morphine for adults with moderate to severe pain from traumatic injury. No economic evaluations or evidence-based guidelines regarding the use of ketamine in adult patients who have suffered painful and traumatic brain and eye injuries were identified. Indexing Status Subject indexing assigned by CRD MeSH Humans; Ketamine; Wounds and Injuries Language Published English Country of organisation Canada English summary An English language summary is available. Address for correspondence Canadian Agency for Drugs and Technologies in Health (CADTH), 865 Carling Avenue, Suite 600, Ottawa, Ontario Canada, K1S 5S8 Email: requests@cadth.ca AccessionNumber 32014000787 Date abstract record published 10/07/2014 |