Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Negative pressure wound therapy for managing diabetic foot ulcers: a review of the clinical effectiveness, cost-effectiveness, and guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions The evidence presented in this report supports greater clinical efficacy of negative pressure wound therapy over other conventional treatments of diabetic foot ulcers. Conclusions are associated with a degree of uncertainty due to small sample sizes and potential for bias in the trials on which the evidence is based. There was no evidence identified suggesting an increased frequency of adverse events associated with negative pressure wound therapy. The majority of analyses also suggest that negative pressure wound therapy is more cost-effective than appropriate comparators, however the evidence also suggests this may not be the case in every healthcare setting and that improvements in efficacy estimates are needed to improve the accuracy of cost-effectiveness analysis. Identified guidelines suggest considering negative pressure wound therapy for diabetic foot ulcers, although the most recent Canadian guidelines identified cite a lack of evidence to support any recommendations regarding the use of negative pressure wound therapy. Indexing Status Subject indexing assigned by CRD MeSH Canada; Cost-Benefit Analysis; Diabetic Foot; Negative-Pressure Wound Therapys; Pressure; Safety; Treatment Outcome; Wound Healing Language Published English Country of organisation Canada English summary An English language summary is available. Address for correspondence Canadian Agency for Drugs and Technologies in Health (CADTH), 865 Carling Avenue, Suite 600, Ottawa, Ontario Canada, K1S 5S8 Email: requests@cadth.ca AccessionNumber 32015000182 Date abstract record published 04/03/2015 |