Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Hypoglossal nerve stimulation (Inspire Upper Airway Stimulation; Inspire Medical Systems Inc.) for treatment of obstructive sleep apnea. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2014 Authors' conclusions Obstructive sleep apnea (OSA) is a chronic disorder affecting 2% to 4% of adults. It is characterized by repetitive collapse of the oropharyngeal airway during sleep, with resultant nocturnal hypoxemia, recurrent arousals from sleep, daytime sleepiness, apnea (cessation of breathing), hypopnea (shallow breathing), hypoxia (low blood oxygen concentration), hypercapnia (high blood carbon dioxide level), and loud snoring. Untreated OSA is more common in the aged and in obese and overweight patients and is associated with daytime sleepiness, fatigue, insomnia, decreased quality of life, and increased healthcare utilization. The apnea hypopnea index (AHI), which expresses the number of apnea and hypopnea events per hour of sleep, is frequently measured in patients with OSA. Moderate to severe OSA is defined by an AHI of > 15 events per hour during sleep. The oxygen desaturation index (ODI) is the number of desaturations of 4% below the baseline level per hour during sleep. Nightly use of continuous positive airway pressure (CPAP) is the standard of care for patients with moderate to severe OSA. However, despite many redesigns by manufacturers aimed at increasing patient comfort, adherence to CPAP therapy is low. Indexing Status Subject indexing assigned by CRD MeSH Electric Stimulation Therapy; Humans; Hypoglossal Nerve; Implantable Neurostimulators; Inhalation; Sleep Apnea, Obstructive Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc., 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218 Email: hayesinfo@hayesinc.com AccessionNumber 32015000347 Date abstract record published 16/03/2015 |