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Oncogenetic testing for persons with hereditary endocrine cancer syndromes |
Vlayen J, Bex M, Bravenboer B, Claes K, Lapauw B, Persu A, Poppe K, Ullman U, Van Maerken T, Vroonen L, Poppe B |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Vlayen J, Bex M, Bravenboer B, Claes K, Lapauw B, Persu A, Poppe K, Ullman U, Van Maerken T, Vroonen L, Poppe B. Oncogenetic testing for persons with hereditary endocrine cancer syndromes. Brussels: Belgian Health Care Knowledge Centre (KCE). KCE Reports 242. 2015 Authors' objectives At present, eight genetic centres are recognized in Belgium. However, no national guideline exists on the indications for genetic testing, and most centres follow their own protocols. Therefore, uniform criteria are needed for the identification and referral of patients to genetic centres for counselling, possibly followed by germline mutation analysis. It is important to provide such guidance to all clinicians active in the field. This guideline is timely because the new nomenclature, introduced on 1/1/2013, for genetic tests (article 33) and the agreement on genetic testing consultation led to redistribute the NIHDI budget between genetic counselling (€4,288 millions) and laboratory procedures (€37,795 millions). There is a need to standardise
the use of these tests and base their use on available evidence. Early identification of persons at risk makes the initiation strategies possible that may reduce morbidity or be lifesaving, including enhanced surveillance and prophylactic surgery. It may also help the patient in making decisions concerning preconception and antenatal screening and reproduction in general. Indexing Status Subject indexing assigned by CRD MeSH Adrenal Gland Neoplasms; Biomarkers, Tumor; Carcinoma; Endocrine Gland Neoplasms; Genetic Predisposition to Disease; Genetic Testing; Humans; Multiple Endocrine Neoplasia; Parathyroid Neoplasms; Pituitary Neoplasms; Thyroid Neoplasms Language Published English Country of organisation Belgium English summary An English language summary is available. Address for correspondence Belgian Health Care Knowledge Centre (KCE), Administrative Centre Botanique, Doorbuilding (10th floor), Boulevard du Jardin Botanique 55, B-1000 Brussels, Belgium tel: +32 2 287 33 88 fax: +32 2 287 33 85 Email: info@kce.fgov.be AccessionNumber 32015000834 Date abstract record published 02/07/2015 |
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