Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation San Miguel L, Vlayen J, De Laet C. Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer – a Rapid Assessment. Brussels: Belgian Health Care Knowledge Centre (KCE). KCE Reports 237. 2015 Authors' objectives The aim of this report is to assess the clinical effectiveness and costeffectiveness of selected gene expression profiling (GEP) and expanded immunohistochemistry (IHC) tests compared to alternative risk assessment methods for early breast cancer patients. Authors' conclusions Although there is good evidence proving the prognostic ability of these tests further research is needed to clarify what their clinical utility is. Such research should also reduce the current uncertainties surrounding the
potential cost-effectiveness of these tests. Indexing Status Subject indexing assigned by CRD MeSH Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Gene Expression Profiling; Immunohistochemistry; Prognosis; Sensitivity and Specificitys Language Published English Country of organisation Belgium English summary An English language summary is available. Address for correspondence Belgian Health Care Knowledge Centre (KCE), Administrative Centre Botanique, Doorbuilding (10th floor), Boulevard du Jardin Botanique 55, B-1000 Brussels, Belgium tel: +32 2 287 33 88 fax: +32 2 287 33 85 Email: info@kce.fgov.be AccessionNumber 32015000836 Date abstract record published 03/07/2015 |