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Development, validation and evaluation of an instrument for active monitoring of men with clinically localised prostate cancer: systematic review, cohort studies and qualitative study |
Simpkin A, Rooshenas L, Wade J, Donovan J, Lane J, Martin R, Metcalfe C, Albertsen P, Hamdy F, Holmberg L, Neal D, Tilling K |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Simpkin A, Rooshenas L, Wade J, Donovan J, Lane J, Martin R, Metcalfe C, Albertsen P, Hamdy F, Holmberg L, Neal D, Tilling K. Development, validation and evaluation of an instrument for active monitoring of men with clinically localised prostate cancer: systematic review, cohort studies and qualitative study. Health Services and Delivery Research 2015; 3(30) Authors' objectives The aims of this project were to review how prostate-specific antigen (PSA) has been used in AM/AS programmes; to develop and test the validity of a new model for predicting future PSA levels; to develop an instrument, based on PSA, that would be acceptable and effective for men and clinicians to use in clinical practice; and to design a robust study to evaluate the cost-effectiveness of the instrument. Authors' conclusions Patients and clinicians found that the instrument provided additional, potentially helpful, information but were uncertain about the current usefulness of the risk model we developed for routine management. Comparison of the model with other monitoring strategies will require clinical outcomes from ongoing AM/AS studies. Indexing Status Subject indexing assigned by CRD MeSH Male; Prostate; Prostatic Neoplasmss; Reproducibility of Results; Risk Assessment; Survival Analysis; Watchful Waiting Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence HS&DR Programme, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, University of Southampton, Alpha House, Enterprise Road, Southampton, SO16 7NS, UK Tel: +44 23 8059 4304
Email: hsdrinfo@southampton.ac.uk AccessionNumber 32015000915 Date abstract record published 10/08/2015 |
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