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Belimumab para el tratamiento del Lupus Eritematoso Sistémico [Belimumab for the treatment of Systemic Lupus Erythematosus] |
Secco A, Augustovski F, Pichon-Riviere A, García Martí S, Alcaraz A, Bardach A, Ciapponi A, López A, Rey-Ares L |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Secco A, Augustovski F, Pichon-Riviere A, García Martí S, Alcaraz A, Bardach A, Ciapponi A, López A, Rey-Ares L. Belimumab para el tratamiento del Lupus Eritematoso Sistémico. [Belimumab for the treatment of Systemic Lupus Erythematosus] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No. 425. 2015 Authors' conclusions There is evidence of high methodological quality, showing that belimumab has a mild/moderate efficacy in the treatment of adult patients with autoantibody-positive systemic lupus erythematosus and high level of disease activity in spite of standard treatment. It is not recommended for those patients with severe central nervous system involvement and/or severe lupus nephritis. The international guidelines recommend it as an alternative in these types of patients and the health sponsors surveyed (U.S.) cover it. However, its use is not recommended by health technology assessments from countries such as the United Kingdom, Scotland or Canada, because of its uncertain effectiveness and cost-effectiveness. Indexing Status Subject indexing assigned by CRD MeSH Antibodies, Monoclonal, Humanized; Humans; Lupus Erythematosus, Systemic Language Published Spanish Country of organisation Argentina English summary An English language summary is available. Address for correspondence Institute for Clinical Effectiveness and Health Policy, Viamonte 2146 - 3 Piso, C1056ABH Ciudad de Buenos Aires, Argentina Tel: +54 11 49 66 00 82 Fax:+54 11 49 53 40 58 Email: info@iecs.org.ar AccessionNumber 32015001155 Date abstract record published 12/11/2015 |
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