Forty-three case series (3,600 patients) that assessed PGP were included. Thirty-five of these case series assessed SGP and 31 assessed FP.
The meta-analysis showed that PTFE grafts gave 5-year PGP rates of 30.5% (95% CI: 22.9, 38.2), SGP rates of 39.7% (95% CI: 28.9, 50.5) and FP rates of 55.7% (95% CI: 45.9, 65.5).
The funnel plot was symmetrical, suggesting that publication bias was unlikely.
The Weibull models adequately fitted the random-effects plots. The sensitivity analysis with the models showed an absolute decrease at the 5-year follow-up of 2.9% for PGP, 3.0% for SGP and 4.9% for FP. Assumptions about loss to follow-up were the main contributors to such decreases: 94% for PGP, 97% for SGP and 96% for FP.
The subgroup analyses showed that the pooled estimates were slightly higher for PTFE grafts with adjunctive procedures, compared with PTFE grafts alone. At 18 months, PGP was 56.8% (95% CI: 49.9, 63.6) for PTFE with adjunctive procedures (27 studies) versus 45.3% (95% CI: 35.8, 54.8) for PTFE alone (13 studies).
Higher quality studies showed higher rates of PGP and FP but not SGP (the results were reported).