Seven cohort studies were included in this review (n=2,200, exposed n=642, non-exposed n=1,558). No significant heterogeneity was noted for any of the analyses. No significant differences in any of the adverse pregnancy outcomes studies were found between exposed and non-exposed groups of women.
Congenital abnormalities (seven studies): OR 1.16 (95% CI 0.76 to 1.77, p=0.57).
Still birth (five studies): OR 2.38 (95% CI 0.65 to 8.72, p=0.32).
Spontaneous abortion (four studies): OR 1.14 (95% CI 0.65 to 2.01, p=0.73).
Preterm delivery (five studies): OR 1.35 (95% CI 0.85 to 2.13, p=0.26).
Low birth weight (three studies): OR 0.93 (95% CI 0.46 to 1.85, p=0.96).