A total of six RCTs were included in the review (n=316 scars). Four of these RCTs scored 3 out of a possible 5 points on the Jadad scale, whilst the remaining trials scored 1 and 4 points each. Concealment of allocation was unclear in all but one trial, in which it was considered adequate.
Meta-analysis of four RCTs (n=158) indicated a small but statistically significant decrease in scar height for the pressure garment therapy group (standardised mean difference -0.31 (95% CI: -0.63, 0.00), p=0.05). No statistically significant benefit of pressure garment therapy was observed for the primary outcome of global scar appearance, or the other secondary outcomes (vascularity, pliability, colour).
Only one trial reported on potential adverse events, finding no differences in pain or pruritis between pressure garment therapy and control groups.