Twenty-five studies (n=5,221 patients, range 19 to 935) were included. Studies were uncontrolled and appeared to be case series.
Successful complete cure en-bloc resections: The pooled proportion was 58.66% (95% CI 47.14 to 69.71). There was evidence of statistical heterogeneity (result not reported) and a random-effects model was used to combine the results. There was no evidence of publication bias as shown by the funnel plot and Begg-Mazumdar test (p=0.17).
Successful en-bloc resections: Using a random-effects model, the pooled proportion was 62.85% (95% CI 51.50 to 73.52).
Results from the subgroup analyses showed that the proportion of both successful cure en-bloc resections and successful en-bloc resections increased as sample sizes increased.