IPD was available from 5,467 patients in three randomised trials. Two trials allowed crossover whereby patients randomised to the selective strategy would receive intervention (depending on pre-discharge tests).
The routine invasive strategy reduced cardiovascular death (hazard ratio 0.83, 95% CI 0.68 to 1.01) or nonfatal myocardial infarction (hazard ratio 0.77, 95% CI 0.65 to 0.90) in comparison to a selective invasive strategy (combined hazard ratio 0.81, 95% confidence interval 0.71 to 0.93). There were 2.0% to 3.8% absolute reductions in cardiovascular death or myocardial infarction in low and intermediate risk patients and an 11.1% risk reduction in highest risk patients.
Other outcomes were reported.