Twenty-three studies were included in the review (n=807 patients). Sample size ranged from 13 to 88 patients.
There was statistically significant underestimation of right ventricular end-systolic volume by 3D echocardiography compared with MRI (WMD -5.5mL, 95% CI -7.6 to -3.4; I2=91%). Right ventricular end-diastolic volume was also significantly underestimated (WMD -13.9mL, 95% CI -17.7 to -10.1; I2=96%), as was ejection fraction (WMD -0.9%, 95% CI -1.8 to -0.1; I2=80%).
Subgroup analyses found that there was greater underestimation of volumes in studies where the mean age of participants was below 18 years and in studies where the mean end-diastolic volume was over 200mL.
Results of regression analyses were also reported.