Eighteen studies (n=1,481 participants, 1,442 masses analysed). Sample sizes ranged from 37 to 136 patients. Two of the included studies were blinded and 11 were prospective studies with consecutive recruitment. All studies had complete verification using the reference standard and all reported adequate details of both the index test and reference standard.
The pooled estimate of the sensitivity of MRI for differentiating borderline or malignant ovarian tumours from benign lesions was 92% (95% CI 89 to 94) and the pooled estimate of specificity was 85% (95% CI 82 to 87). The pooled estimates of positive and negative likelihood ratios were 6.7 (95% CI 4.3 to 10.5) and 0.1 (95% CI 0.08 to 0.15). There was significant between-study heterogeneity for all estimates.
The sensitivity analysis did not change estimates of test accuracy.
Data on positive and negative predictive values and area under the SROC curve were reported.