Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation EsophyX system with SerosaFuse fastener (EndoGastric Solutions) for endoluminal repair for gastroesophageal reflux disease (GERD) Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2012 Authors' conclusions Gastroesophageal reflux disease (GERD) is caused by recurring reflux of the stomach contents into the esophagus, which results in the classic symptoms of heartburn. GERD affects 25% to 40% of the world population. This chronic disorder is associated with significant morbidity, substantially impacting quality of life (QOL), and the possibility of mortality from complications. Initially GERD is treated with lifestyle modification, and dietary changes. If symptoms are persistent, drug therapy including acid suppressants and antacids, histamine-2 receptor antagonists, or proton pump inhibitors are prescribed. The pharmaceutical agents can lose their effectiveness over time, requiring progressively higher dosing. Adults affected by GERD who no longer respond adequately to drugs or those who wish to discontinue use of these medications have the option of laparoscopic antireflux surgery, commonly referred to as laparoscopic Nissen fundoplication. While this surgery has long proven to be effective in treating the disease, the procedure is invasive and potential side effects of the fundoplication procedure may compromise otherwise excellent postsurgical results. A transoral incisionless fundoplication procedure using the EsophyX system with SerosaFuse
fasteners was developed to mimic antireflux surgery, as a minimally invasive alternative procedure with potentially fewer side effects. Indexing Status Subject indexing assigned by CRD MeSH Fundoplication; Gastroesophageal Refluxs; Hydrogen-Ion Concentration Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc., 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218 Email: hayesinfo@hayesinc.com AccessionNumber 32013000225 Date abstract record published 27/03/2013 |