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Evaluation and treatment of tinnitus: comparative effectiveness |
Pichora-Fuller MK, Santaguida P, Hammill A, Oremus M, Westerberg B, Ali U, Patterson C, Raina P |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichora-Fuller MK, Santaguida P, Hammill A, Oremus M, Westerberg B, Ali U, Patterson C, Raina P. Evaluation and treatment of tinnitus: comparative effectiveness. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 122. 2013 Authors' objectives A review was undertaken to evaluate the peer-reviewed literature on three areas of tinnitus management for the following Key Questions (KQs): (1) measures used to assess patients for management needs (KQ1); (2) effectiveness of treatments (KQ2); and (3) identification of prognostic factors (KQ3). Authors' conclusions There is low strength of evidence (SOE) indicating that cognitive behavioral therapy interventions improve tinnitus-specific quality of life relative to inactive controls. For pharmacological interventions, SOE is low for improvements to subjective loudness from neurotransmitter drugs versus placebo; insufficient for antidepressants, other drugs, and food supplements with respect to subjective loudness; and insufficient for all other outcomes. There is insufficient SOE to suggest that medical interventions improve outcomes relative to inactive controls; sleep and global quality of life were not evaluated for medical interventions. The SOE for the adverse effect of sedation in pharmacological studies was judged insufficient. Future research should address the substantial gaps identified for KQ1 and KQ3. For KQ2, future research should concentrate on improving collection of adverse effects, calculating sample size, and specifying doses for interventions. Indexing Status Subject indexing assigned by CRD MeSH Diagnosis, Differential; Tinnituss Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence AHRQ, Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA Email: AHRQTAP@ahrq.hhs.gov AccessionNumber 32013000716 Date abstract record published 14/10/2013 |
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