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Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study |
de Graaf H, Sukhtankar P, Arch B, Ahmad N, Lees A, Bennett A, Spowart C, Hickey H, Jeanes A, Armon K, Riordan A, Herberg J, Hackett S, Gamble C, Shingadia D, Pallett A, Clarke S C, Henman P, Emonts M, Sharland M, Finn A, Pollard A J, Powell C, Marsh P, Ballinger C, Williamson P R, Clarke N M & Faust S N |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation de Graaf H, Sukhtankar P, Arch B, Ahmad N, Lees A, Bennett A, Spowart C, Hickey H, Jeanes A, Armon K, Riordan A, Herberg J, Hackett S, Gamble C, Shingadia D, Pallett A, Clarke S C, Henman P, Emonts M, Sharland M, Finn A, Pollard A J, Powell C, Marsh P, Ballinger C, Williamson P R, Clarke N M & Faust S N. Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study. Health Technology Assessment 2017; 21(48) Authors' objectives To assess the overall feasibility and inform the design of a future randomised controlled trial (RCT) to reduce the duration of intravenous (i.v.) antibiotic use in paediatric acute osteomyelitis (OM) and septic arthritis (SA). Authors' conclusions A future RCT would need to recruit from all tertiary and most secondary UK hospitals. Clinicians have implemented early oral switch for selected patients with simple disease without formal clinical trial evidence of safety. However, the current criteria by which decisions to make the oral switch are made are not clearly established or evidence based. Indexing Status Subject indexing assigned by CRD MeSH Anti-Bacterial Agentss; Arthritis, Infectious; Infusions, Intravenous; Osteomyelitis Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NETSCC, Health Technology Assessment, Alpha House, University of Southampton Science Park, Southampton, SO16 7NS UK Tel: +44 23 8059 5586 Email: hta@hta.ac.uk AccessionNumber 32013000976 Date abstract record published 17/12/2013 |
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