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Improving antibiotic prescribing for uncomplicated acute respiratory tract infections |
McDonagh M, Peterson K, Winthrop K, Cantor A, Holzhammer B, Buckley DI |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation McDonagh M, Peterson K, Winthrop K, Cantor A, Holzhammer B, Buckley DI. Improving antibiotic prescribing for uncomplicated acute respiratory tract infections. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 163. 2016 Authors' objectives To assess the comparative effectiveness of interventions for improving antibiotic use for acute respiratory tract infections (RTIs) in adults and children. Authors' conclusions The best evidence supports the use of specific education interventions for patients/parents and clinicians, procalcitonin in adults, and electronic decision support to reduce overall antibiotic prescribing (and in some cases improve appropriate prescribing) for acute RTIs without causing adverse consequences, although the reduction in prescribing varied widely.
Other interventions also reduced prescribing, but evidence on adverse consequences was lacking, insufficient, or mixed. Future studies should use a complex intervention framework and better evaluate measures of appropriate prescribing, adverse consequences such as hospitalization, sustainability, resource use, and the impact of potential effect modifiers. Indexing Status Subject indexing assigned by CRD MeSH Acute Disease; Anti-Bacterial Agents; Humans; Prescriptions; Respiratory Tract Infections Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence AHRQ, Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA Email: AHRQTAP@ahrq.hhs.gov AccessionNumber 32016000216 Date abstract record published 03/02/2016 |
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