Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSRIC. Doxorubicin-eluting beads (DC Bead, DC Bead M1 and Radiopaque DC Bead) for hepatocellular carcinoma. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016 Authors' objectives Hepatocellular carcinoma is the most common type of liver cancer. Most cases of hepatocellular carcinoma are caused by cirrhosis, a condition associated with damage and scarring to the liver. This is often caused by excessive alcohol intake or having long term infections with hepatitis B or C. It is more common in men than women and typically affects older people.
DC Bead consists of beads that are designed to release doxorubicin, a chemotherapy drug, at a slow rate at the site of the cancer. This is delivered directly to the hepatic artery, a blood vessel that supplies blood to the liver. Studies have shown that DC Bead delivers doxorubicin to the tumour without the drug spreading to healthy tissue.
DC Bead is already used to treat hepatocellular carcinoma in the UK. Indexing Status Subject indexing assigned by CRD MeSH Anthracyclines; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Doxorubicin; Humans; Liver Neoplasms Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NIHR Horizon Scanning Research&Intelligence Centre, University of Birmingham, Institute of Applied Health Research, Public Health building, Edgbaston, Birmingham B15 2TT
Tel: 0121 414 9077 Email: nihrhsc@contacts.bham.ac.uk AccessionNumber 32016000427 Date abstract record published 04/03/2016 |