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NIHR HSRIC. Doxorubicin-eluting beads (DC Bead, DC Bead M1 and Radiopaque DC Bead) for hepatocellular carcinoma. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016
Hepatocellular carcinoma is the most common type of liver cancer. Most cases of hepatocellular carcinoma are caused by cirrhosis, a condition associated with damage and scarring to the liver. This is often caused by excessive alcohol intake or having long term infections with hepatitis B or C. It is more common in men than women and typically affects older people.
DC Bead consists of beads that are designed to release doxorubicin, a chemotherapy drug, at a slow rate at the site of the cancer. This is delivered directly to the hepatic artery, a blood vessel that supplies blood to the liver. Studies have shown that DC Bead delivers doxorubicin to the tumour without the drug spreading to healthy tissue.
DC Bead is already used to treat hepatocellular carcinoma in the UK.
Subject indexing assigned by CRD
Anthracyclines; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Doxorubicin; Humans; Liver Neoplasms
Country of organisation
An English language summary is available.
Address for correspondence
NIHR Horizon Scanning Research&Intelligence Centre, University of Birmingham, Institute of Applied Health Research, Public Health building, Edgbaston, Birmingham B15 2TT
Tel: 0121 414 9077 Email: firstname.lastname@example.org
Date abstract record published