Study designs of evaluations included in the review
Randomised trials were eligible.
Specific interventions included in the review
Regimens of either oral doxycycline (100 mg twice daily for 7 days) or oral azithromycin (1 g once) were eligible.
Participants included in the review
Male and non-pregnant females aged greater than 15 years, who were being treated for Chlamydia trachomatis (CT) cervicitis (females) and urethritis (males), were eligible.
Outcomes assessed in the review
The studies had to assess microbial cure at follow-up. Microbial cure was defined as CT negativity in the biological assay. Adverse events were separated by type (see 'Data extraction' field).
How were decisions on the relevance of primary studies made?
Both authors independently evaluated all trials comparing doxycycline with azithromycin.