This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database.
Harstall C. Mammography screening: mortality rate reduction and screening interval. Edmonton: Alberta Heritage Foundation for Medical Research (AHFMR). AHFMR HTA Report 21. 2000
The Alberta Clinical Practice Guidelines Program, as part of its process for updating the clinical practice guidelines (CPG) on breast cancer screening, requested a review of the current evidence. The three objectives of this assessment are to determine the available scientific evidence on:
1. The effective time interval for mammography screening in asymptomatic women aged 50 to 69 years
2. The effective screening interval in asymptomatic women between the ages of 40 and 49 years
3. The mortality rate reduction of mammography screening in asymptomatic women aged 40 to 49 years.
- Results from RCTs and meta analyses have demonstrated a significant reduction in breast cancer mortality among screened women aged 50 years and over with screening intervals ranging from 12 months to 33 months.
- Effectiveness of screening asymptomatic women aged 40 to 49 years remains unresolved.
- Uncontrolled, retrospective studies, considered to be low level of evidence, were available to determine the appropriate screening intervals for different age groups. These studies provided inconclusive evidence.
- Efficacy of annual mammography screening in asymptomatic women commencing at ages 40 and 41 years will be addressed by a UK RCT.
INAHTA brief and checklist
Subject indexing assigned by CRD
Breast Neoplasms /diagnosis; Mammography; Mass Screening
Country of organisation
An English language summary is available.
Address for correspondence
1200, 10405 Jasper Avenue, Edmonton, Alberta, Canada, T5J 3N4. Tel: +1 780 448 4881; Fax: +1 780 448 0018 Email: email@example.com
Date bibliographic record published
Date abstract record published