Randomised controlled trials (RCTs) of exercise training for six to 18 year olds with medically diagnosed cystic fibrosis were eligible for inclusion. The intervention was required to last for at least two weeks, be structured and described in sufficient detail to be replicated. Studies were required to compare exercise training versus a differing modality of exercise and/or usual care (without additional formal exercise). Studies that were of inspiratory muscle training only or a single session of exercise were excluded.
Participants in the included studies had mild, moderate or severe cystic fibrosis. Mean age was 11 to 14 years. Mean height was 143cm to 160cm. Mean weight was 36kg to 48kg. Schwachman scores ranged from 67 to 90. Interventions included aerobic and anaerobic exercise and resistance training, which varied in intensity, duration, length of sessions and setting. Controls received usual care and activities. Outcomes reported in the review were pulmonary function and fitness (aerobic, strength and anaerobic). Measures used included forced vital capacity (FVC), forced expired volume in one second (FEV1%), maximum volume of oxygen consumed, change in muscle force during leg extension and change in peak power output.
A single reviewer selected the studies.