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NIHR HSRIC. Naldemedine for opioid-induced constipation in adults. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016
Opioids are a class of drugs that are commonly prescribed for pain. Constipation is a side effect that affects nearly all patients taking opioid treatment. There has been an increase in the use of opioids to treat chronic pain in recent years. Current treatment for opioid-induced constipation often involves laxatives. But, it has been estimated that 50–80% of people taking laxatives for opioid-induced constipation get only a limited improvement in symptoms.
Naldemedine is a new drug for the treatment of opioid-induced constipation in adults that is taken as a tablet once a day. If it is licensed for use in the UK, naldemedine may offer an additional treatment option for adults with this debilitating condition.
Subject indexing assigned by CRD
Adult; Analgesics, Opioid; Constipation; Humans; Narcotic Antagonists
Country of organisation
An English language summary is available.
Address for correspondence
NIHR Horizon Scanning Research&Intelligence Centre, University of Birmingham, Institute of Applied Health Research, Public Health building, Edgbaston, Birmingham B15 2TT
Tel: 0121 414 9077 Email: email@example.com
Date abstract record published