This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database.
HAYES, Inc. Comparative effectiveness review of topical chlorhexidine gluconate for preoperative skin antisepsis. Lansdale: HAYES, Inc. Directory Publication. 2017
Skin preparation products are used prior to surgery to quickly eliminate a wide range of microbes and provide a continuously high level of antimicrobial action for an extended duration of time.
Skin preparation products are used prior to surgery to quickly eliminate a wide range of microbes and provide a continuously high level of antimicrobial action for an extended duration of time. The most common skin preparation agents currently used in the United States for antisepsis prior to surgery are products that contain iodophors or chlorhexidine gluconate (CHG).
Iodophors have been the standard topical antiseptic agents used to cleanse the skin prior to surgery. CHG is a newer antiseptic agent that has antimicrobial advantages over iodophors. It has not been determined which agent is the most effective at preventing surgical site infections (SSIs). In addition, these antiseptic agents may be in either aqueous- or alcohol-based solutions, which may further enhance their antiseptic properties. Key Questions:
Is CHG effective in reducing the incidence of SSIs in adults undergoing clean, cleancontaminated, or contaminated surgery? How does CHG compare with iodophors in reducing the incidence of SSIs? Are topical CHG and iodophor products safe in adults who are undergoing surgery? Have definitive patient selection criteria for topical CHG products been established?
Subject indexing assigned by CRD
Antisepsis; Chlorhexidine; Humans; Skin; chlorhexidine gluconate
Country of organisation
An English language summary is available.
Address for correspondence
HAYES, Inc., 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218 Email: firstname.lastname@example.org
Date abstract record published