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| [Efficacy of atomoxetine and methylphenidate in attention deficits hyperactivity disorder in adults: a rapid review] |
| Jang BH, Lee HY, Jung YJ, An JH |
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Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Jang BH, Lee HY, Jung YJ, An JH. [Efficacy of atomoxetine and methylphenidate in attention deficits hyperactivity disorder in adults: a rapid review] Seoul: National Evidence-based Healthcare Collaborating Agency (NECA). NECA-C-12-007. 2012 Authors' conclusions The research was carried out using the basic existing systematic review framework suggested by the Agency for Healthcare Research and Quality (AHRQ 2009). A final twenty-one existing systematic reviews evaluated the adequacy and quality of the literature using AMSTAR (Assessment of Multiple Systematic Reviews). However, twenty of them did not score high enough grades in their quality, and the last one had a high grade but the research results were unacceptable because they could have been out of date since the review was published in 1999. Thus, instead of using the existing systematic reviews, a de novo systematic review of randomized controlled trials on atomoxetine/methylphenidate was performed, according to the framework of this research.
To conduct the de novo rapid review, a total of 39 studies were selected. After reviewing these studies on atomoxetine and methylphenidate, most of the studies concluded that both medications effectively relieved adult ADHD symptoms. There were some adverse events such as nausea, headache, and loss of appetite, but the symptoms were not severe, and these symptoms disappeared after stopping the medication. Thus, using these two medications for adult ADHD is considered appropriate. Indexing Status Subject indexing assigned by CRD MeSH Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivitys; Methylphenidate; Propylamines Country of organisation South Korea English summary An English language summary is available. Address for correspondence National Evidence-based Healthcare Collaborating Agency (NECA), Changkyung B/D 9F, Wonnam-dong 28-7, Jongno-gu, Seoul, South Korea
Email: hta_neca@neca.re.kr AccessionNumber 32013000535 Date abstract record published 22/07/2013 |
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