This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database.
CADTH. Negative pressure wound therapy for managing diabetic foot ulcers: a review of the clinical effectiveness, cost-effectiveness, and guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014
The evidence presented in this report supports greater clinical efficacy of negative pressure wound therapy over other conventional treatments of diabetic foot ulcers. Conclusions are associated with a degree of uncertainty due to small sample sizes and potential for bias in the trials on which the evidence is based. There was no evidence identified suggesting an increased frequency of adverse events associated with negative pressure wound therapy. The majority of analyses also suggest that negative pressure wound therapy is more cost-effective than appropriate comparators, however the evidence also suggests this may not be the case in every healthcare setting and that improvements in efficacy estimates are needed to improve the accuracy of cost-effectiveness analysis. Identified guidelines suggest considering negative pressure wound therapy for diabetic foot ulcers, although the most recent Canadian guidelines identified cite a lack of evidence to support any recommendations regarding the use of negative pressure wound therapy.
Subject indexing assigned by CRD
Canada; Cost-Benefit Analysis; Diabetic Foot; Negative-Pressure Wound Therapys; Pressure; Safety; Treatment Outcome; Wound Healing
Country of organisation
An English language summary is available.
Address for correspondence
Canadian Agency for Drugs and Technologies in Health (CADTH), 865 Carling Avenue, Suite 600, Ottawa, Ontario Canada, K1S 5S8 Email: firstname.lastname@example.org
Date abstract record published