This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database.
McDonagh M, Peterson K, Winthrop K, Cantor A, Holzhammer B, Buckley D. Interventions to improve appropriate antibiotic prescribing for uncomplicated acute respiratory tract infections. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 163. 2015
To assess the comparative effectiveness of interventions for improving antibiotic use for acute respiratory tract infections (RTIs) in adults and children.
. The best evidence supports the use of specific education interventions for patients/parents and clinicians, procalcitonin in adults, and electronic decision support to reduce overall antibiotic prescribing (and in some cases improve appropriate prescribing) without causing adverse consequences, although the reduction in prescribing varied widely. Other interventions also reduced prescribing but evidence on adverse consequences was lacking, insufficient, or mixed. Future studies should use a complex intervention framework and better
evaluate measures of appropriate prescribing, adverse consequences such as hospitalization, sustainability, and resource use and the impact of potential effect modifiers.
Subject indexing assigned by CRD
Anti-Bacterial Agents; Clinical Trial; Humans; Prescriptions; Respiratory Tract Infections
Country of organisation
An English language summary is available.
Address for correspondence
AHRQ, Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA Email: AHRQTAP@ahrq.hhs.gov
Date abstract record published